The sponges are too large for most pipes, so you'll probably need to use a lot of soap and water (you should probably add even more soap than they recommend for tighter fits) for most cases and hope it comes out intact. Unfortunately, this size also means relatively quick sponge deterioration, which means that you'll need to rinse out everything at least twice, unless you like having little red clumps of sponge in your keys. I'm not sure about the purpose of the straight sponge, other than pushing the end of the other one into pipes. At some point I got worried the sponge would break off from its cable and stay in one of the smaller pipes, but luckily it didn't.
The mouthpiece cleaner is great.