I bought this docking station for one reason only - to be able to easily connect and disconnect peripherals and USB devices from my Macbook. I'm happy to say that PureLink VL-220 does this perfectly; it even powers the computer, so it's really is a matter of (dis)connecting a single cable.
Just be aware of the fact that if you're using a Mac, you _probably_ won't be able to use 2 displays in extend mode if you connect them both to the dock, I think that's even stated in the manual somewhere.